![]() In these cases, a CBC can be used to monitor these drug treatments. ![]() Abnormal platelet production due to defective megakaryocytes can result in a high MPV. Also note, that low numbers of large platelets may not increase the MPV (which represents the mean) above reference intervals. ![]() Further, some therapies (e.g., chemotherapy) can affect production of blood cells and some medications can decrease counts overall. Causes of an increased MPV are given below. Similarly, if someone is receiving treatment for a blood-related disorder, a CBC will be ordered regularly to determine if the treatment is effective. If someone has been diagnosed with a disease that is known to affect blood cells, a CBC will be ordered regularly to monitor the condition. A healthcare professional may run a CBC as a part of a routine health examination or when a person has signs and symptoms that may be related to disorders that affect blood cells, such as: Assessment of platelets is typically done in a comprehensive blood count (CBC), which also measures features of red and white blood cells. Typically, the results of a MPV test are compared to the platelet count and the platelet distribution width (PDW) to provide a doctor with more information regarding the underlying condition. If your Platelet count is in between 150 thou/uL and 450 thou/uL and your MPV is in between 6.8 fL and 10. Low MPVs indicate smaller platelets, meaning the individual is at risk for a bleeding disorder. High Platelet count and low MPV can be caused by many reasons. ![]() High MPVs mean the platelets are larger, which could put an individual at risk for heart attack or stroke. Their primary function, along with the coagulation factors, is to stop bleeding by clumping and clotting blood vessel injuries. Platelets, also called thrombocytes, are one of three types of cells found in the blood. Mean platelet volume is a test that measures and calculates the average size of the platelets. ![]()
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